A Munir, N Leech, KP Windebank, J McLelland, GL Jones, D Mitra, A Jenkins, R Quinton
Journal Issue: 
Volume 42: Issue 4: 2012



Langerhans cell histiocytosis can involve single or multiple organ/tissue systems and may go undiagnosed for years until it enters the clinician’s differential diagnosis framework. We report on a young patient who initially presented with diabetes insipidus and subsequently with pyrexia of unknown origin. She progressed from single system Langerhans cell histiocytosis to multisystem involvement and remains in long-term remission following chemotherapy.

Keywords Langerhans cell histiocytosis, diabetes insipidus

Declaration of Interests No conflicts of interest declared.