This symposium covered a range of common neurological conditions of interest both to the general physician and neurologist. Neurological problems presenting to acute physicians were highlighted: stroke risk and prevention following transient ischaemic attacks; an update on stroke thrombolysis; when to refer stroke patients to regional neuroscience centres; and epilepsy and its neurological and cardiac mimics. At the other end of the spectrum, the management of chronic neurological disease, including Parkinson’s disease, and end-of-life neurology care were reviewed. Updates on developing patient-centred services for people with neurological impairments were presented. Finally there was a practical guide to driving regulations in a variety of clinical scenarios.