Cases of the quarter: The importance of pursuing a histological diagnosis in the HIV setting

A 40-year-old heterosexual African man was admitted with fever, night sweats  and  lymphadenopathy.  His  human  immunodeficiency  virus  antibody  test was  positive.  Initial  lymph  node  biopsy  revealed  reactive  hyperplasia  only. He  was  empirically  treated  for  tuberculosis.  However,  symptoms  persisted  and a  repeat  lymph  node  biopsy  was  obtained,  which  confirmed  Hodgkin’s  disease. This  emphasises  the  need  to  pursue  histological  diagnosis  in  such  patients  with persisting symptoms.