Obesity and the Risk of Malignancy: An Evolving Saga

Worldwide, the prevalence of both obesity and cancer are rising. So far, there is an association between obesity and an increased risk of at least 20 different cancers and this number is increasing. The mechanism behind obesity increasing the risk of cancer varies. The importance of looking at all aspects of obesity, such as hip to waist ratio, body fat distribution and waist circumference, in addition to BMI has been acknowledged in order to further understand these mechanisms.

Scleroedema of Buschke in conjunction with ovarian carcinoma: rare association of a rare disease

Scleroedema is a rare clinical condition characterised by diffuse woody induration of skin commonly associated with diabetes mellitus, infections and monoclonal gammopathy. Its association with ovarian malignancy has not been reported. We report a case of a 56-year-old female with rapidly progressing skin thickening of limbs, face and trunk for 1 year and abdominal distension for 3 months. Patient had thickened skin, mask-like facies and ascites on examination. Atypical cells were seen in ascitic fluid.